VanGenes Cell-Free DNA Preservative Tube (RUO)

The VanGenes Cell-Free DNA Preservative Tube is designed for direct whole blood collection, enabling the isolation, stable storage, and transportation of nucleated cell genomic DNA or plasma cell-free DNA. (Note: This product is intended for research use only and is not for medical diagnosis.)

Principle of the VanGenes Cell-Free DNA Preservative Tube
The detection and analysis of nucleic acids in blood, particularly cell-free DNA (cfDNA) in plasma, represent an emerging and reliable field in disease diagnosis. While healthy individuals typically have low levels of cfDNA in plasma, changes in circulating cfDNA levels are associated with various clinical conditions.

Research has shown that the VanGenes Cell-Free DNA Preservative Tube is a convenient, rapid, and sensitive tool that can be applied in molecular diagnostics and detection of tumors, as well as in prenatal diagnosis of fetal genetic disorders. During the analysis of plasma cfDNA, sample handling, transportation, and processing are prone to contamination, which may lead to the breakdown of nucleated blood cells and the subsequent release of genomic DNA. Additionally, cfDNA degradation due to nuclease activity can pose significant challenges.

The additives in the VanGenes Cell-Free DNA Preservative Tube stabilize nucleated blood cells, preventing the release of genomic DNA, and inhibit nuclease-mediated degradation of cfDNA, thereby ensuring the overall stability of cfDNA.

The VanGenes Cell-Free DNA Preservative Tube not only protects cell surface antigenicity and maintains cell morphology but also enhances the extraction, detection, and analysis of cfDNA. Samples collected in the VanGenes Cell-Free DNA Preservative Tube (available in 5mL and 10mL sizes, product codes 207121 and 207122) can be stored stably at 6–37°C for up to 14 days and transported at room temperature for 72 hours. This flexibility allows customers to adapt to specific sample requirements, making sample collection, transportation, and storage more convenient.

The VanGenes Cell-Free DNA Preservative Tube is suitable for clinical research, drug discovery, and enhanced diagnostic testing.

VanGenes Cell-Free DNA Preservative Tube Specifications